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Cannabis (Cannabissativa L.) is an annual plant, which can grow and spread in tropical or sub-tropical regions with a height of one to five meters (Emcdda, 2015). Human selection is done for various uses and climate-influenced natural selection produces various varieties and chemical compositions. Analysis of the chemical content of cannabis (Cannabis sativa L) as a result of confiscation in the Aceh Regional Police, namely Lhokseumawe Regional Police, Pidie Regional Police, East Aceh Regional Police (Idi Rayeuk), Benar Meriah Regional Police and Central Aceh Regional Police (Takengon) were conducted by GC-MS method. Cannabis was extracted with n-hexane and marijuana extract was analyzed by GC-MS. ?9-THC and CBC compounds were found in all marijuana samples, CBN was found in 4 origin areas except Central Aceh Police Station, 2-Metoxy-5-isopropilaxy-7-propenylnaphthquinone was found in two police stations from Pidie Police and Central Aceh District Police. The biggest concentration of ?9-THC is 80.92% of the East Aceh Police Station; ?9-THCV is from two original police stations, namely East Aceh Police and Benar Meriah Police; CBN is the biggest 14.25% of Polres Benar Meriah; The biggest CBC is 10.98 from the East Aceh District Police..